Noninvasive, convenient and practical means of risk stratification have been important in the management of patients with acute myocardial infarction. Electrocardiogram-derived ejection fraction has been proposed as a readily available means of determining risk for cardiovascular outcomes. This was a prospective cohort study of patients who had acute myocardial infarction admitted from June 1, 2015 to June 30, 2016. Ejection fraction from the patient's baseline electrocardiogram and echocardiogram were compared and correlated with in-hospital morbidity and mortality after discharge. Computed ejection fraction from the ECG formula by Krake7 yielded a mean of 51%. These results were not statistically different compared to the 2D echocardiogram derived ejection fraction with a mean of 51% (P >0.05). However, 2D echocardiogram derived ejection fraction was more accurate in determining LV function (AUC of 0.82) compared to ECG. While the patients were admitted, 74% of the patients were found to have preserved ejection fraction as computed from the ECG. Occurences of arrhythmia, stroke and renal failure were not statistically different between patients with low EF and preserved EF (p Value >0.05) but those with low EF had greater odds of developing stroke and renal failure (OR 1.5). On follow-up, mortality was not statistically different between those with low and preserved EF (P value >0.05). However, those with low EF had greater odds of mortality in the succeeding one, three and six months after hospital discharge (OR >1.0).