Background: Severe coronary artery disease in patients with a markedly depressed left ventricular function is associated with a poor prognosis. Even though coronary angioplasty (PCI) has been offered as an alternative to bypass surgery, the role of PCI in the treatment of CAD patients with severe LV dysfunction has not been well defined. The aim of the present study is to compare the clinical outcomes in CAD patients with LV dysfunction (EF<40%) who will undergo complete revascularization via PCI vs. CABG.
Methods: Eighty CAD patients with a left ventricular ejection fraction of <40% who underwent CABG (n=40) were analyzed.
Results: Eighty-eight percent of CABG and 83% of PCI group has improved anginal status. Functional classification likewise improved in both groups, with 25% of patients in CABG and 40% of patients in PCI group were classified to FC I. Only a minority of patients in PCI group (13%) remained to be FC III. Death occurred in 11% of patients, 13% in CABG group and 10% in the PCI group. Neither groups reported a repeat incidence of myocardial infarction, nor a need for a repeat revascularization procedure.
Conclusion: These data suggest that PCI may be an effective treatment option or coronary artery disease patients with left ventricular dysfunction.