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Submitted: 16 May 2007 Modified: 02 November 2016
HERDIN Record #: PCHRDPC051585

The clinical profile and outcome of PTCA (with or without stent) in diabetic and non-diabetic patients with coronary artery disease: The Philippine Heart Center experience.

Raul D Jara,
Ramoncito B Tria,
Kar Rillera-Posadas

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BACKGROUND: Retrospective case-control study conducted at Philippine Heart Center (PHC). This study aims to determine the clinical profile, outcome and survival between diabetic and non-diabetic patients who underwent PTCA.


METHODS AND RESULTS: A total of 128 patients who underwent angioplasty from 1995-2000 were included with 60 diabetic and 68 non-diabetic patients. Males predominated with ages between 58-59 years. Mean duration of Diabetes Mellitus (DM) was eight years. Among the diabetic patients, 63 percent were smokers, with 32 percent presenting with hypercholesterolemia and 55 percent were found to be hypertensive. However, in the non-diabetic group, 8 percent were obese and 47 percent were hypertensive. Both the diabetic and non-diabetic groups had predominantly one-vessel involvement. Mean Ejection Fraction (EF) of 57 percent in diabetic and 59 percent in non-diabetic group were found in this study. Furthermore, diabetic patients were more likely to be in the New York Heart Association (NYHA) functional class (FC) II on admission, while non-diabetic patients were in the NYHA FC I. Complication rate of 40 percent was noted in the DM group whereas 24 percent was found in the non-DM group. The case success rate was 95 percent in the DM group and 96 percent in the non-DM group (p=NS). Three patients (5 percent) in the DM and three cases (4 percent) in the non-DM group died during hospitalization. Over-all major adverse cardiac events were not different between the two groups (16 percent vs. 8 percent p=NS).


CONCLUSION: Long-term and event-free survival rates were not significantly different between the diabetic and non-diabetic patients (81 vs. 89 percent) up at six years follow-up. (Author)

Publication Type
Journal
Title
Philippine Heart Center Journal
Publication Date
January-December 2002
Volume
9
Page(s)
14-18
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No. 40 Fulltext pdf (Request Document)