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Submitted: 16 May 2007 Modified: 06 April 2013
HERDIN Record #: PCHRDPC000410

A local prototype pulse-duplicator machine in the Philippine Heart Center: An experimental study.

Cecilio G. Celino,
Christopher C. Cheng,
Avenilo P. Aventura,
Ludgerio D. Torres ,
Florencio G. Castillo ,
Patricia J. Agunod

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A local prototype pulse-duplicator machine was developed at our center with the purpose of testing locally assembled bioprosthetic valves prior to processing and implantation into human subjects
METHODS: The valve tester was developed from a single roller pump within a housing that propels priming fluid continuously in a pulsatile flow. The tubings were connected into a plastic cylindrical chamber where the valves were mounted. The cylinder was connected to an afterload tubing which drains the fluid into a reservoir which brings back the fluid to the pump. At a fixed pulsatile rate, the afterload pressures were increased at increments to a range of 0 to 300 mmHg. The tested valves can be directly observed during each cycle for any anatomic or functional defect. Seven biologic valves were individually subjected into the valve tester. At the end of each experiment, anatomic and mechanical defects detected were torn leaflets, loose cusps, asynchronous or poor leaflet motions, or a combination of the above. These valves were considered not suitable for implantation after subjecting them into high pressures
CONCLUSIONS: Our local prototype pulse-duplicator machine could serve as an inexpensive valve tester by direct visualization of the valves to screen our locally fabricated bioprosthesis prior to clinical use.

Publication Type
Journal
Publication Sub Type
Journal Article, Original
Title
Philippine Journal of Cardiology
Frequency
Quarterly
Publication Date
July-September 1999
Volume
27
Page(s)
83-85
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No.44 Fulltext Print Format (Request Document)
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